Cobra Golf L4V F $399 Cobra pushed the absolute limit of clubhead size, coming within a blade of Kentucky blue grass of the 5"x5" limit. It's geared toward the player that swings hard and has a draw bias, so it might take some of the patheticness out of that slice you're currently rocking.
Callaway I-Mix System $500 and up The I-Mix isn't really one driver, as much as it's a collection of about 1,600 different head and shaft combinations. They took their FT-I and FT-5 club heads and packaged them with a special tool that lets players change shafts on a whim. If you have the dough, you can buy different shafts to suit different courses or conditions. You can even get a replacement head for when you drop your old one in the parking lot and scrape the hell out of it.
Cleveland HiBORE XLS "You have a big face," doesn't usually sound like a compliment, but when it comes to drivers it's akin to saying, "Hey, nice butt." The XLS is 13% bigger than its predecessor and has "stability foils" around the perimeter so the head won't get all wonky mid-swing. They also help line up the ball with the club head. No whiffers.